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KMID : 1098420140220010001
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Korean Journal of Medicinal Crop Science
2014 Volume.22 No. 1 p.1 ~ p.7
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Triterpenoid Saponin Contents of the Leaf, Stem and Root of Codonopsis lanceolata
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Kim Ji-Ah
Moon Heung-Kyu
Choi Yong-Eui
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Abstract
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Codonopsis lanceolata (Campanulaceae) has been used in traditional medicines, as its roots contain several kinds of 3,28-bidesmosidic triterpenoid saponin with high medicinal values. In this study, we induced hairy root-derived transgenic plants of C. lanceolata and analyzed triterpenoid saponins from the leaf, stem and root. Transgenic plants were regenerated from the hairy roots via somatic embryogenesis. The saponins are lancemaside A, B and E, foetidissimoside A, and aster saponin Hb. Transgenic plants contained richer triterpenoids saponin than wild-type plants. Major saponin lancemaside A was the most abundant saponin in the stem from transgenic-plant, 4.76 ㎎·1?1 dry stem. These results suggest that transgenic plants of C. lanceolata could be used as medicinal materials for the production of triterpene saponins.
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KEYWORD
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Codonopsis lanceolata, Triterpenoid Saponin, Lancemaside A, B, E, Foetidissimoside A, Aster Saponin Hb
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